Anti bacterial activity of bovine milk lactoferrin against some mastitis causative pathogens with special regard to mycoplasmas.
Abstract:
From a private farm a total number of 36 milk samples were collected from a clinically mastitic cows. The bacteriological examination showed isolation of mycoplasma bovis, S. aerus, E. coli, P.aeruginosa and S.agalactiae as single or mixed infection. Lactoferrin concentrations (LFC) in the clinical mastitic cow’s milk were higher (1.4 to 3.2mg/ml) than normal milk. The average LFC in milk from infected cows with M.bovis or S.aerus was obviously high either in single or mixed infection. The total number of 36 clinically mastitic milk samples was positive to M.bovis antibodies by using ELISA test while only 38.9% of the examined samples were positive to M.bovis by cultivation method. The most interesting finding in this assay was the antibacterial effect of lactoferrin (LF) on M.bovis, M.bovigentalium as well as P.aeruginosa and S.agalactiae originally isolated from bovine mastitis. Inhibitory activity of LF was seen in all tested strains. The most effective inhibitory activity of LF was seen against P.aeruginosa and S.agalactiae, followed by inhibitory activity of LF on the two mycoplasama strains. Inhibition of growth by LF was concentration dependent. The concentration of 1mg / ml was generally too low for a marked inhibitory effect.
Publication year 2010
Pages 97-105
Organization Name
Country Egypt
serial title مجلة الميكروبولوجيا الدولية
Volume 1 . 3
Author(s) from ARC
Publication Type Journal
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