Effect of Branched Chain Amino Acids on Ovulation Rate in Native Ewes
Abstract: SUMMARY:The purpose of this study was To measure the effect of branched chain amino acids (BCAA) leucine, isolcucinc and valine infused to the ewes during late stage of the luteal phase on ovulation rale and whether this effect is associated with alteration in circulating concentrations of reproductive and metabolic hormones and glucose or not. Oestrus was synchronized with vaginal sponge for 13 days. At day zero (day of ovulation) eight ewes were randomly assigned into two equal groups, control ( n = 4), treated ( n = 4) groups, at day 9 of the ocstrous cycle, control group received saline solution while treated one was infused with a mixture of three amino acids leucine, isolcucinc and valine for 5 days. Ovaries were examined by laparoscope at days zero and day 7 of the next oestrus cycle, blood was collected at days 6. 9, 12 and 15 of the same estrous cycle for measuring reproductive (FSH- estiadiol-progcsteronc), metabolic (Insulin, IGF-1, Leptin) hormones and glucose. BCAA infusion increased ovulation rate, reduced mean concentrations of FSH and estradiol especially at days 9 and 12 of the cycle, while increased mean concentrations of IGF I, Leptin and glucose especially at days 9 and 12 of the cycle and of insulin especially at days 12 and 15 of the cycle. On the other hand, the mean concentrations of progesterone were similar to that of control group. We concluded that BCAA infusion to the ewes during late luteal phase increase ovulation ratle and her an effect on ovulation rate may not involve an increase in mean concentrations of FSH but may involve an increasing of the response of growing follicles to elevate concentrations of glucose. Insulin, Leptin and IGF-1 acting directly at the ovarian level.
Publication year 2007
Pages 209-222
Availability location معهد بحوث التاسليات الحيوانية
Availability number
Organization Name
Author(s) from ARC
External authors (outside ARC)
    ايمن مصطفى سيد معهد الانتاج الحيوانى
Agris Categories Animal physiology - Reproduction
Proposed Agrovoc BRANCHED CHAIN;
Publication Type Researsh & Applied Activities
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