Effects of Camphor as A New Method for Treatment of Puerperal Endometritis in Buffalo
Abstract: SUMMAR:
The present work studied the effects of intrauterine infusion of camphor oil on uterine involution, ovulation cyclicity, first postpartum estrus, days open, histopathology of the uterus, progesterone and estradiol-17 profile of the first postpartum estrus as well as milk residue of camphor in buffalo. Starting at the 7lh day postpartum, 25 muitiparous buffalo were divided into 3 groups. The 1st group (n=5) was the normal puerperium control buffalo. The 2nd group (n=10) was normal pureperium buffalo given only intrauterine infusion of 100 ml camphor oil 10% three times with 48 hours interval to study it's pharmacological effects on reproduction. The 3rd group (n=10) was postpartum buffalo (7-14 days postpartum) suffered from 3rd degree endometritis and treated with 100 ml camphor oil 10% three times, 48 hours interval, then given 1 dose of 50 ml oxytetracycline 3%. The intrauterine infusion of camphor oil to the postpartum buffalo at the 7th day significantly (P<0.005) enhanced the uterine involution with no alterations in reproductive efficiency. Histopathological examination of uterine biopsy by the 41 week postpartum showed that the uterine mucosal epithelium appeared tall columnar with few desquamated cells and the uterine glands were also lined by columnar epithelium. Camphor significantly (P< 0.05) decreased the peak of serum concentration of estradiol -17 β during the estrous phase without affecting serum progesterone concentration. The gas chromatography analyses of camphor oil in milk of buffalo in 2nd group ranged from 15.54 to 280.3 ng/ml and all traces of camphor disappeared from milk after 24 hours from the last treatment. Treatment of buffalo suffered from 3rd degree of endometritis by intrauterine infusion of camphor oil and oxytetracycline gave good results. There was no significant
difference in the measured reproductive parameters and hormones betweenthe treated as well as the normal puerperium control group. Microscopical examination of the uterine samples by the 5th week postpartum showed that the surface epithelium was mostly covered by tall columnar epithelial cells.
The chromatographic analyses of camphor in the buffalo's milk in the 3rd
group was within the range of 66.36-157 ng/ml and disappeared from milk
12hours after the last treatment.
Keywords: Camphor, Puerperal Endometrirtis, Buffalo
Publication year 2005
Pages 167-188
Availability location معهد بحوث التناسليات الحيوانية الهرم
Availability number
Organization Name
Author(s) from ARC
Agris Categories Animal physiology - Reproduction
Proposed Agrovoc Camphor, Puerperal Endometrirt;Camphor, Puerperal Endometrirt;
Publication Type Researsh & Applied Activities
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