Effect Somatotropin administration on reproductive hormones and some metabolicparameters of cycling Egyptian ewes some metabolicparameters of cycling Egyptian ewes on reproductive hormones and some metabolicparameters of cycling Egyptian ewes

Abstract: Summary
The objective of this study to evaluate the effects of recombinant bovine somatotropin (rbST) on reproductive hormones and metabolites related to ovarian activity during luteal phase with two different does of somatotropin.This study carried out on fifteen sexually mayure local crossed ewes (Bark×Rahmani) of 2-3 years old and average weight 50-60kg .Estrous cycle was synchronized by two doses of PGF2α (Prosolvin) injection of 1ml of mg into vaginal submucsa 10 days apart .Ewes were randomly allotted into three groups of 5 ewes, the first was kept as control ,the second and the third groups were subcutaneously injected with 2.5 and 5 mg of somatotropin/day respectively , and continued to cover complete estrous cycle .Individual blood samples were collected daily throughout the experimental periods .High dose somatotropin has an overall increment effect on serum progesterone level on comparison with each of control and low dose somatotropin group ..Also, both dose of somatotropin have an overall increasing effect on serum estradiol 17β and IGF1 levels .Anrostenedione level was lower in treated ewes compared with control .Moreover, high dose of rbST treated group has an overall increment effect on serum glucose and cholesterol levels. High density lipoprotein (HDL) level in high rbST dose group was higher than that of each other groups. Both of overall means of low density lipoprotein (LDL) of control and high dose rbST groups were higher than that of low dose somatotropin one .All previous parameters were dependent on the day of luteal phase.
We concluded that higher dose of rbST(5mg/day) subcutaneously injection has positive effect on the reproductive hormones progesterone, estradiol and IGF1.The same effect of high dose of rbST was clear on the levels of serum glucose and lipid profiles. So we recommended using 5 mg of rbST injection to cycling ewes to optimize reproductive management and fertility via its increasing effect on hormone and metabolites which led to enhance follicular growth and ovarian activity .








Publication year 2011
Pages 262-247
Availability location المجلة
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    فتحى الفار
Agris Categories Animal physiology and biochemistry
Publication Type Researsh & Applied Activities
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