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Factors Affecting the Stability of Clostraidial Toxins and Toxoids and Ther Effect on the Immune Response
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Abstract: The prepared different clostridial toxins gave best permanent toxicity when stored at 40C after adding stabilizer and adjusting the pH value to 8.0 (for C.perfringens type B, C.septicum and C.novyi type B toxins) and at 6.5 (for C.perfringens type D and C.tetani toxins) at the end of their fermentation period. Immune response of polyvalent clostridial vaccine prepared from these toxins gave higher antibody titers in immunized sheep using vaccine without pH controlling (about6.5) and had stabilizer in their content than, these with or without stabilizer and their pH value was adjusted to 8.0
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| Publication year |
2002
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| Pages |
315-321
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| Availability location |
(معهد بحوث الامصال واللقاحات البيطرية)
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| Availability number |
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| Organization Name |
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| City |
المنوفية
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| serial title |
المؤتمر العلمى الثانى كلية طب بيطرى ـ جامعة المنوفية
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| Department |
Anaerobic Bacterial Vaccine Research
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| Author(s) from ARC |
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| Agris Categories |
Animal diseases
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| Proposed Agrovoc |
Clostridial toxins;C.perfringens;
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| Publication Type |
Conference/Workshop
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