Trials for production and evaluation of combined vaccine from rift valley fever, pasteurella haemolytica and pasteurella multocida inactivated with binary ethleneimine in cattle
Abstract: Nowadays , the direction of the scientist is to produce combined vaccines as being economic.In this study, there was a trial to produce a combined Rift valley Fever, Pasteurella multocida and Pasteurella haemolytica oil adjuvant vaccine and inactivated with binary ethyleneimine (BEI),Also, the immune response of cattle was studied.We used twelve susceptible 6 months old calves classfied into four groups. Each group continued three calves.The first group was vateaccind with monovalent Rift Valley Fever vaccine,second group was vaccinated with conlined Rift Valley fever and pasteurella vaccine, the third group was vaccinated with pasteurella haemolytica and pasteurella multocida vaccine alone, and the forth group was left as a control non-vaccinated. The first three groups recieved a booster dose after one month. The animals were observed and their immune response were investigated for 6 months. The results revealed that, concerning the immune response to Pasteurellae antigens, there was no competition with Rift Valeey Fever antigen as non-significant differences were noted between the serological and immunological test results of the single and combined vaccines. All vaccinated animals acquired a protective level of antibodies against RVF virus or Pasteurella strain. It can be concluded that the combined RVF and pasteurella oil adjuvant vaccine can be used effectively in controlling both diseases in cattle.
Publication year 2000
Availability location معهد بحوث الامصال و اللقاحات البيطرية - القاهرة - ش السكة البيضاء - العباسية
Availability number
Organization Name
City cairo
serial title Egypt journal Agriculture, Research
Author(s) from ARC
External authors (outside ARC)
    فريد فؤاد زكي المعمل المركزي للرقابة على المستحضرات الحيوية البيطرية
Agris Categories Animal diseases
AGROVOC
TERMS		 Pasteurella haemolytica. Pasteurella multocida. Rift valley fever virus. Vaccines.
Proposed Agrovoc Binary ethylynamine;
Publication Type Journal
↑