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Effect of haemoprotozoa infection on the immune response of cattle immunized with combined inactivated respiratory (Pneumo-3) vaccine
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Abstract: Immunosuppressive effect of haemoprotozoal infection was investigated in cattle vaccinated with Pneumo-3 vaccine. In field, eighty pregnant cows were immunized with the vaccine and screened for babesia and theileria infection. Six and tweenty cows out of the eighty were found infected with Theileria annulata (T. annulata) and Babesia bovis (B. bovis), respectively. While the other fifty four cows were free from haemoprotozoa. Specific humoral immune responses post vaccination was evaluated by monitoring the developed neutralizing antibody titre against different vaccinal antigen component (BVD, IBR and PI-3) are were higher in non-infected cows than that infected with T. annulata or B. bovis. Passive immunization detected in the blood of the newly born calves was similarly affected by haemoprotozoa infection of their dams.
Experimentally infected calves with acute T. annulata or B. bovis followed by Pneumo-3 vaccination, showed reduction in the immune response toward vaccinal component. It is concluded that immunosuppression due to haemoprotozoa infection (Theileria or Babesia) should be considered before vacctionation campaign.
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| Publication year |
2004
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| Pages |
386-396
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| Availability location |
مكتبة معهد بحوث الامصال واللقاحات البيطرية.
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| Availability number |
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| Organization Name |
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| City |
الزقازيق
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| serial title |
7th Vet.Med.Zag.Conference
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| Author(s) from ARC |
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| External authors (outside ARC) |
أ.د. حسين متولى غالى
معهد بحوث الأمصال واللقاحات البيطرية
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| Agris Categories |
Animal diseases
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| Proposed Agrovoc |
Haemoprotozoa;Pneumo-3;
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| Publication Type |
Conference/Workshop
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