Preparation and evaluation of Inactivated respiratory syncytial virus vaccine
Abstract: This study aimed to prepare an inactivated bovine respiratory syncytial virus (BRSV) vaccine. The virus was propagated in different available types of tissue culture. This vaccine was prepared using Madin Dabry Bovine kidney cell line (MDBK) which produced high titer reached to 107 TCID50 / 0.1 mol. Aluminum hydroxide gel was used as an adjuvant in a concentration of 10%.
Prepared BRSV vaccine was proven to be safe after being inoculated in mice and guinea – pigs, and safety tested calves remained well allover the experiment. Challenge test was conducted 21 days post – vaccination and it proved potency of the vaccine.
Concerning seroconversion, the vaccinated calves were serologically protected for six months post – vaccination.
Publication year 2000
Pages 2155-2167
Availability location معهد بحوث الامصال واللقاحات البيطرية-الدقى
Availability number
Organization Name
City القاهرة
serial title Egypt.J.Agric.Res
Author(s) from ARC
External authors (outside ARC)
    سيد محمد زيدان معهد بحوث الأمصال واللقاحات البيطرية
    ايمان كامل احمد قاسم معهد بحوث الأمصال واللقاحات البيطرية
Agris Categories Animal diseases
AGROVOC
TERMS		 Pneumovirus.
Proposed Agrovoc Darby bovine kidneyMDBK)(;
Publication Type Journal
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