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Trials for the preparation of a lyophilized formalin inactivated foot and mouth disease vaccine and its application in guinea pigs in comparison with the liquid vaccine
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Abstract: A lyophilized formalin- inactivated foot and mouth disease virus (FMOV) vaccine was prepared by the propagation of the virus on monolayer of BHK cells. Its titre was 109 TCID50/ml. and 0.5% gelatin has been chosen as a stabilizer for the freeze dried vaccine.
Potency test in guinea pigs showed protection percentage of 100, 100, 50 and zero when using the liquid vaccine, undiluted to
¼, 1/16 and 1/64 respectively, while the percentages were 100, 88.89, 71.43, 33.34 and when using the dried vaccine undiluted, diluted to 1/4 , to 1/16, to 1/64 and to 1/256 respectively.
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| Publication year |
1993
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| Pages |
456-460
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| Availability location |
معهد بحوث الامصال واللقاحات البيطرية-ش السكة البيضاء-العباسية-القاهرة
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| Availability number |
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| Organization Name |
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| City |
القاهرة
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| serial title |
الجمعية الطبية المصرية
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| Author(s) from ARC |
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| Agris Categories |
Animal diseases
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AGROVOC
TERMS |
Foot and mouth disease.
Guinea pigs.
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| Proposed Agrovoc |
fmdv;lyophilized formalin;
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| Publication Type |
Journal
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