Evaluation of bivalent inactivated oil adjuvant African Horse sickness vaccine In guinea pigs and mice

Abstract: In this study, neutralizing antibody response in guinea pigs and mice inoculated by African horse sickness (AHS) bivalent oil adjuvant vaccine was similar when compared serologically with that in the horse. There fore , using G. pigs and mice may be a method of great value in potency test for routine immunization. Potency test of the prepared vaccine using an immunization challenge protocol in adult mice was studied, using challenge virus with 100 , 50 and 25 LD50. the highest protection level (95%) was with the dilution of 50 LD50 / 0.05 ml.
Publication year 2007
Pages 4
Organization Name
City بني سويف
serial title Beni Suef Veterinary medical journal
Author(s) from ARC
Agris Categories Animal diseases
AGROVOC
TERMS
Adjuvants. African horse sickness. Guinea pigs. Mice. Vaccines.
Publication Type Journal