The role of equine herpsvirus-1 antisera in preventing abortion in laboratory animals as a model
Abstract: The study was designed to detect the efficacy of passive protection using immune serum against local strain of EHV-1 to prevent abortion in susceptible mares, so the laboratory animals (mice, rabbits) were used as a model, preparation of the immune sera was done using different types of viral antigens. Experimentally, it was clear that inactivated ( at 56 oC) egg propagated viral antigen was better than tissue culture antigen. Also, transfer of 0.2 and 0.3 ml polyclonal hyperimmune serum protected 75% and 100% of inoculated mice respectively after challenge. While, 1 ml was protect inoculated rabbits (100%). In conclusion, transfer of immune against EHV-1 succeed to prevent abortion in laboratory animals at last third of pregnancy. This is a step to be tested in mares.
Publication year 2007
Availability location معهد بحوث الامصال و اللقاحات البيطرية - القاهرة - ش السكة البيضاء - العباسية
Availability number
Organization Name
City المنصورة
serial title المؤتمر العلمي الخامس لكلية الطب البيطري - جامعة المنصورة
Author(s) from ARC
External authors (outside ARC)
    د.نشأت بطرس اسكندر معهد بحوث الأمصال واللقاحات البيطرية
Agris Categories Animal diseases
AGROVOC
TERMS		 Abortion. Equine herpesvirus. Rabbits. Rats.
Proposed Agrovoc Antisera;
Publication Type Conference/Workshop
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