Evaluation of local immunity induced by Fowl cholera vaccines in Ducks

Abstract: A local immune response against fowl cholera disease could be induced in group of Duck vaccinated via air sac on intranasally by formalized heat inactivated on sonicated P.multocida vaccines. By conducting indirect fluorescent antibody tevhnique (IFAT) secretory IgA antibodies could be detected in tracheal or lung tissue sections. also these secretory IgA antibodies were detected in nasal swabs collected from vaccinated ducks. Anti P.multocida IgG antibodies could also be detected in tissue sections of vaccinates.Histopathological examination of trachea and lungs of vaccinated ducks revealed cellular infilteration with lymphocytes and monocytes documenting the local immune response. Alsa circulating IgG antibodies were detected by ELISA in sera of vaccinated ducks. Data obtained indicated teh superiority of sonicated vaccine. Vaccination against fowl cholera via air sac or intranasally is not a substitution for routine bacterin vaccination. but it rather can be considered as a complementary mean and also a substitution of using hazardous living vaccines.
Publication year 2005
Pages 6
Availability location معهد بحوث الامصال و اللقاحات البيطرية - القاهرة - ش السكة البيضاء - العباسية
Availability number
Organization Name
City القاهرة
serial title جمعية المجلة الطبية البيطرية
Author(s) from ARC
External authors (outside ARC)
    ساهر مكين جرجس معهد بحوث الأمصال واللقاحات البيطرية
Agris Categories Animal diseases
AGROVOC
TERMS
Ducks. Fowl cholera. Immunofluorescence. Vaccines.
Publication Type Journal