Production and evaluation of the immune efficiency for inactivated rift valley fever vaccine adjuvanted with ims 3013.
Abstract: In this work seventeen balady sheep were divided into 6 groups, the first group (GI) was vaccinated S/C with binary inactivated RVF vaccine with 50% IMS 3013, the second group(G2)was vaccinated S/C with binary inactivated RVF vaccine containing 0.5% saponin with 50% IMS 3013,the third group (G3) was vaccinated S/C with binary inactivated RVF vaccine with 25% IMS3013, the fourth group (G4) was vaccinated S/C with binary inactivated RVF vaccine containing 0.5% saponin with 25% IMS3013, the fifht group (G5) was vaccinated S/C with inactivated RVF vaccine with aluminum hydroxide gel while the sixth group(G6)left as a control. the results revealed that RVF inactivated vaccine with IMS3013 either 50% or 25% give higher level of antibody and reaching its protective level earlier than RVF inactivated vaccine with aluminum gel and the best vaccine is RVF inactivated vaccine contaning 0.5% saponin with IMS3013 where ED50 equal 0.0008/ml and gave a higher level of antibody all over teh period of the test compared with that of other vaccinated groups when tested by lymphocyte transformation assay using MMT staning procedure and serum neutralization test.
Publication year 2005
Pages 107
Availability location معهد بحوث الامصال واللقاحات البيطرية.
Availability number
Organization Name
City اسيوط
serial title مجلة اسيوط الطبية البيطرية
Author(s) from ARC
External authors (outside ARC)
    للي صبحي سلامة معهد بحوث الأمصال واللقاحات البيطرية
Agris Categories Animal diseases
AGROVOC
TERMS		 Saponins.
Proposed Agrovoc IMS 3013;Binary ethyleneimine;Aluminum hydroxide;
Publication Type Journal
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