Some factors affecting the keeping quality of Bovine ephemeral fever vaccine

Abstract: An inactivated and live attenuated bovine ephermal fever (BEF) locally produced vaccines were exposed to different temperatures for different periods. The ability of the inactivated vaccine to generate neutralizing antibodies in vaccinated cattle and hamster was evaluated. The virus neutralization test showed that such vaccine was able to induce virus-neutralization antibodies in vaccinated cattle and hamster up to 12, 9 and 1 months post preservation at 4,25 and 37˚ respectively. On the other hand, the titration of live attenuated lyophilized vaccine revealed that the virus vaccine could survive without any loss in its infectivity titer up to 1 month at 0 and 4˚ C and up to 12 and 18 month at -20˚ and 70˚C respectively then began to decline very slowly and lost its infectivity titer completely after 3 and 72 hours and 1 week at 56, 37 and 25˚C respectively. So, it is clear that the best preservation temperature is 4 ˚ C for the inactivated vaccine and -70˚C for the live attenuated vaccine.
Publication year 2003
Pages 715-722
Availability location معهد بحوث الامصال واللقاحات البيطرية-القاهرة - ش السكة البيضاء - العباسية ص ب 131
Availability number
Organization Name
City كفر الشيخ
serial title المؤتمر العلمي الأول
ISSN 1687-1456
Author(s) from ARC
External authors (outside ARC)
    سمير محمد ادريس
Agris Categories Animal diseases
AGROVOC
TERMS
Bovine ephemeral fever virus.
Publication Type Conference/Workshop