Use of BCG vaccine for enhancement the immune response of sheep to Rev.1 vaccination

Abstract: This study was conducted to evaluate the protective effect of Brucella meltensis Rev.1 and use of BCG vaccine as immunostimulant by subcutaneous injection in Guinea pigs. Lab animals were divided into 8 groups: combined Rev.1 and BCG vaccines injected in the 1st group & both vaccines were injected simultaneously in the 2nd group. Three groups sensitized with BCG vaccine then injected with Rev.1 vaccine one week, two week & three weeks intervals respectively. Other two groups were injected with BCG and Rev.1 vaccine individually. The last one was unvaccinated control. All injected animals showed resistance to infection with 16M strain (90%, 80%,80%,60%,70%,0% and 70% respectively).thus animals vaccinated with bivalent Rev.1 and BCG vaccines (in one hot) showed the best protective level to infection.
Publication year 2007
Pages 6-11
Availability location ش السكة البيضاء - العباسية -القاهرة
Availability number
Organization Name
City Giza
serial title The fifth scientific conference animal disease control
Author(s) from ARC
Agris Categories Animal diseases
Proposed Agrovoc BCG;
Publication Type Conference/Workshop