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The potential use of anti- idiotypic antibodies as a serodiagnostic reagent for detection of rinderpest and ppr antibodies
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Abstract: Anti idiotype antibodies (AIA) were prepared to rinderpest (RP) and PPR viruses by using their hyperimmune sera (Id). RP and PPR- AIA were standardized as being used for coating ELISA plates against serial dilutions of their relevant hyperimmune sera. Both types of AIA were utilized as a diagnostic antigens to assay cattle and sheep sera in comparison with the conventional viral antigens. Either RP or PPR – AIA proved to be as potential as their viral antigens in terms of the specificity and the sensitivity upon using as diagnostic antigens. Moreover, RP- AIA managed to detect PPR antibodies with a higher efficacy then RP viral antigen and vice versa. Hence, anti- idiotype antibodies have been displaying a great potentiality in diagnostic purposes over the traditional systems.
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| Publication year |
2001
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| Availability location |
ش السكة البيضاء - العباسية-القاهرة
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| Availability number |
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| Organization Name |
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| City |
cairo
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| serial title |
25th arab veterinary medical congress
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| Author(s) from ARC |
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| Agris Categories |
Animal diseases
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AGROVOC
TERMS |
Antibodies.
Rinderpest.
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| Publication Type |
Conference/Workshop
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