|
|
The use of binary thylenimine and formalin as inactivants for production of inactivated newcastle disease vaccine
|
|
|
Abstract: The use of Binary Ethylenimine as inactivant for Newcastle virus give a promising result as it has no effect on the antiginecity of the virus when used in a concentration of 0.01M or 0.03M at the same time it had completely reduced the virulence of the virus within 6 to 8 hours according to the concentration. This results were superior than teh results obtained when using formaldehyde solution as inactivant in concentration of 0.1% or 0.2% which significantly reduced antigenicity from 1024 to 32 HA titr. The experimental prepared batches of Binary inactivated vaccine as compared with fromalin ianctivated prepared vaccine by different adjuvants (oil-gel) proved that the BEI 0.1M wiht oil as adjuvent was the best as it gives the highest 10g2 HI titer(5.3) as well as the highest protection percentage 94%.
|
| Publication year |
1996
|
| Pages |
157-168
|
| Availability location |
ش السكة البيضاء - العباسية -القاهرة
|
| Availability number |
|
| Organization Name |
|
| City |
Assiut
|
| serial title |
Assiut veterinary medical journal
|
| ISSN |
1012-5973
|
| Author(s) from ARC |
|
| External authors (outside ARC) |
|
| Agris Categories |
Animal diseases
|
AGROVOC
TERMS |
Formaldehyde.
Newcastle disease.
Vaccines.
|
| Publication Type |
Journal
|