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Studies to prepare an inactivated vaccine against gumboro and reo viruses
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Abstract: Gumboro (GD) or infectious bursal disease (IBD) AND REO disease are two viral diseases affecting chicken causing great economic losses. The present work was planned to prepare a combined inactivated oil vaccine.
On the comparison between the potency of IBD and Reo monovalent and combined vaccines,it was found that all vaccines resulted in good protection percentage which was 95% for monovalent IBD. 100% for monovalent reo; 90% for IBD and 93.3% for Reo in the combined vaccine.
Serum neutralization test revealed that specific neutralizing antibodies against IBD and Reo viruses were produced in the sera of vaccinated chicken from the 1st week post vaccination recording a peak titre by the3rd week without any adverse effect of IBD or Reo inactivated viruses on teh immune response to the other. The level of formed antibodies began to decrease in all groups of vaccinated chicken between the 8th to 9th week post vaccination.
Bursal body weight indices and examination did not show any abnormaliites due to any vaccination.
So.it could be concluded that the inactivated IBD and Reo combined vaccine is a safe and potent vaccine protects chicken against the two diseases.
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| Publication year |
1999
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| Pages |
29-43
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| Availability location |
القاهرة - ش السكة البيضاء - العباسية
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| Availability number |
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| Organization Name |
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| City |
المنصورة
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| serial title |
مجلة بحوث العلوم الطبية البيطرية
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| Author(s) from ARC |
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| Agris Categories |
Animal diseases
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AGROVOC
TERMS |
Gumboro disease.
Reovirus.
Vaccines.
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| Publication Type |
Journal
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