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Genomic Comparative Studies On Rinderpest, PPr And Measles Concerning With Their Antigenic Performances
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Abstract: Rinderpest antibodies in sera of vaccinated cattle were detected with rinderpest (RP) and peste des petits ruminants (PPR) viruses but not canine distemper (CD) virus. While, PPR antibodies in immune sheep sera were recognized with the three viruses. But, canine distemper antibodies in sera of immune dogs were detected only with canine distemper and PPR viruses. On reviewing the published nucleotide and deduced amino acid sequences of H,F and NC genes of the three aforementioned morbilli-viruses, it has been noticed that a closer degree of similary was found between RP and PPR viruses than between RP and CD viruses. This gives a clue for more sharing consensus sequences between RP and PPR that might explain their closer antigenic relationship and however, the degree of homology among the three viruses are relatively low especially on the H-gene level as it carries the characteristics epitopes determining host specifity for each virus. These studies might be useful in terms of immunization and sero-surveillance purposes.
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Publication year |
2001
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Pages |
221-228
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Availability location |
القاهرة - ش السكة البيضاء - العباسية
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Availability number |
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Organization Name |
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City |
بنى سويف
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serial title |
second scientific congress proceedings
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Author(s) from ARC |
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Agris Categories |
Animal diseases
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AGROVOC TERMS |
Rinderpest.
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Publication Type |
Journal
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