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The potential use of anti-idiotypic antibodies as a serodiagnostic reagent for detection of rinderpest and PPR antibodies
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Abstract: Anti-idiotype antibodies (AIA) were prepared to rinderpeste (RP) and PPR viruses by using their hyperimmune sera (Id.) RP and PPR – AIA were standardized as being used for coating ELISA plates against serial dilutions of their relevant hyperimmune sera. Both types of AIA were utilized as a diagnostic antigens to assay cattle and sheep sera in comparison with the conventional viral antigens. Either RP or PPR-AIA proved to be as potential as their viral antigens in terms of the specificity and the sensitivity upon using as diagnostic antigens. Moreover, RP – AIA managed to detect PPR antibodies with higher efficacy than RP viral antigen and vice versa. Hence, anti-idiotype antibodies have been displaying a great potentiality purposes over the traditional systems.
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| Publication year |
2001
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| Pages |
145-152
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| Availability location |
القاهرة - ش السكة البيضاء - العباسية
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| Availability number |
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| Organization Name |
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| City |
cairo
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| serial title |
25 th arab veterinary medical congress
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| Author(s) from ARC |
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| Agris Categories |
Animal diseases
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AGROVOC
TERMS |
Antibodies.
Rinderpest.
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| Publication Type |
Journal
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