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Effect of selenium on the immune response of sheep vaccinated with PPR vaccine
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Abstract: Ten balady sheep susceptible to PPR [pestes des petits ruminants] virus were used in a six-month trial to study the effect of selenium on the humoral immune response of PPR vaccine. They were divided into two groups each of five sheep, control group vaccinated subcutanaeously with 1 ml PPR vaccine containing 103 TCID50/ml, test group vaccinated with 1 ml PPR vaccine added to it 5 mg selenium (as sodium selenite dissolved in the diluent). Blood samples were drown weekly for four weeks then two weeks up to 24 weeks post vaccination and assayed for serum selenium concentration, and antibody titres using serum neutralization test and ELISA technique. Compared with those sheep receiving the PPR vaccine alone (control group), sheep received selenium had higher serum selenium concentration and a significant increase in antibody titre during the whole experimental period. Selenium was proved to be immunopotentiating to PPR vaccine in sheep.
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| Publication year |
2001
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| Pages |
136-146
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| Availability location |
القاهرة - ش السكة البيضاء - العباسية
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| Availability number |
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| Organization Name |
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| City |
cairo
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| serial title |
Assiut veterinary medical jornal
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| Author(s) from ARC |
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| Agris Categories |
Animal diseases
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AGROVOC
TERMS |
Immune response.
Sheep.
Vaccines.
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| Publication Type |
Journal
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