Experimental infection of cattle buffaloes and sheep with virulent rinderpest virus

Abstract: 10 cross-breed Friesian cattle, 10 Egyptian water buffaloes and 20 Barki sheep were subcutaneously inoculated with the Egyptian virulent strain of rinderpest virus (Singh, et al., 1967). The haematological and serological parameters were monitored to speculate the changes caused by the virus which might envisage the clinical manifestations shown on the inoculated animals. The morbidity rate was 100% in both cattle and buffaloes. The mortality rates were 100% and 30 %in cattle and buffaloes respectively. Neither morbidities nor mortalities were found among the inoculated sheep. The survived buffaloes developed variable high titers of neutralizing antibodies (150-400), 21 days post inoculation (d.p.i.). However, sheep gave very low neutralizing antibody titers.
In case of cattle, a significant increase in red blood cells (R.B.Cs)., haemoglobin amount (Hb) and packed cell volume (PCV) was observed by the 7th d.p.i. Also, a remarkable decrease in leucocytic count-especially in lymphocytes (lymphopenia) was noticed on the 4th d.p.i. and onward till death.
On the other hand, there was a significant decrease in total protein especially serum albumin which occurred on the 4th d.p.i. But in case of buffaloes, the increase in RBCs count, Hb percent and PCV was comparatively milder and transient ; similary the leucopenia moderate and delayed (9th to 13th d.p.i.) There was mild decrease in blood proteins and serum albumin accompanied by an increase in serum globulin. The inoculated sheep exhibited insignificant changes either in blood picture or blood proteins.
The present study has proved that, cattle and buffaloes are the most susceptible hosts to rinderpest but sheep are either refactory or highly resistant infection.
Publication year 1995
Pages 29-40
Availability location القاهرة - ش السكة البيضاء - العباسية
Availability number
Organization Name
City القاهرة
serial title الجمعية الطبية البيطرية المصرية
Author(s) from ARC
Agris Categories Animal diseases
AGROVOC
TERMS		 Cattle. Morbillivirus. Sheep. Virulent pathogens.
Publication Type Journal
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