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Evaluation of protective immuity induced by a recombinant baculovirus expressing two structural proteins of Bovine Viral Diarhhea virus in calves
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Abstract: Two groups of calves were vaccinated with a double recombinant baculovirus expression product of a previously developed construct(rec-Neo), expressing the nucleoprotein (N) and the envelope glycoprotein (EO) of the NADL strain of bovine viral diarrhea virus (BVDV). The baculovirus expression product, in rec-NEO vaccine, were immunogenic in calves as viral neutralizing antibody(VN-Ab) titers of 2 to 8 were detectable following booster vaccination. Vaccinated and non-vaccinated calves were challenge exposed with either the homologus BVDV1-NADVL or the local heterologous BVDV2-Iman strains. Vaccine-induced immunity conferred partial protection against homologous viral challenge exposure,
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| Publication year |
1999
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| Pages |
163-171
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| Availability location |
القاهرة - ش السكة البيضاء - العباسية
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| Availability number |
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| Organization Name |
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| City |
Cairo
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| serial title |
The egyptian journal of immunology
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| ISSN |
1110-4902
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| Author(s) from ARC |
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| Agris Categories |
Animal diseases
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AGROVOC
TERMS |
Calves.
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| Proposed Agrovoc |
viral diarrhea virus;
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| Publication Type |
Journal
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