Preliminary trials for preparation of tetravalent Inactivated oil vaccine against Newcastle Infectious bronchitis, egg drop syndrome and fowl cholera

Abstract: Inactivated Newcastle disease virus (NDV), infectious bronchitis virus (IBV), egg drop syndrome (EDS) and P. multocida (PM) were incorporated into water in oil emulsion vaccines alone (monovalent) or as in combined (tetravalent) vaccine immunological response to the new tetravalent vaccine was evaluated by injecting groups of susceptible chickens with either tetravalent or monovalent vaccine. Results revealed that humoral immunity with the new tetravalent vaccine were never inferior to those obtain with the monovalent ones. There were no practical differences in the percentage and duration of the protective immunity induced with NDV vaccine and P. multocida vaccine upon challenge with velogenic viscerotropic Newcastle disease virus (VVNDV) or PM antigen. The tetravalent (NDV+ IBV+ EDS and FC) inactivated vaccine was safe, immunogenic and produced satisfactory dual protection against NDV, IBV, EDS and P. multocida infections
Publication year 2003
Pages 393-411
Availability location القاهرة - ش السكة البيضاء - العباسية
Availability number
Organization Name
City Mansoura
serial title The third international scientific conference
Author(s) from ARC
External authors (outside ARC)
    محب عوض
    انصاف خشبة
Agris Categories Animal diseases
Proposed Agrovoc newcastle diesease;
Publication Type Conference/Workshop