Preparation and evaluation of killed NDV vaccine Using new oil adjuvant
Abstract: Preparation of inactivated oil Newcastle disease virus (NDV) vaccine using different new oil adjuvants montanide ISA 70 VG, ISA763A VG and ISA 775 as oil adjuvants in comparison with paraffin oil was carried out. The prepared vaccines with Montanide ISA 70 VG, 763 A VG and 775 VG induced high antibody titers than that induced by vaccines prepared wit paraffin oil when determined by serological tests (HI and SNT). The highest titer observed in prepared vaccine by ISA 70 VG oil adjuvant after 3weeks post vaccination and remained high till 12 weeks post vaccination and has long duration of immunity reached to 12 month with a protective antibody titer and protection against challenge while prepared vaccine by Montonide ISA 763 A VG oil adjuvant reached 10 month with Montanide ISA 775 reached to 9 months, but in paraffin protective antibody titer reached only till 5 month.
Publication year 2008
Pages 95-103
Availability location معهد بحوث الامصال واللقاحات البيطرية
Availability number
Organization Name
City Giza
serial title Veterinary medical journal
Author(s) from ARC
External authors (outside ARC)
    محمد سامي صابر كلية الطب البيطري - جامعة القاهرة
    اسماعيل محمد رضا كلية الطب البيطري - جامعة القاهرة
    سوزان سيد مهدي المعمل المركزي للرقابة على المستحضرات الحيوية
Agris Categories Animal diseases
Publication Type Journal
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