Comparative Studies on Evaluation of an Inactivated Egg Drop Syndrome Vaccine Produced in Duck Embryos Eggs and in Cell Cultures (With 6 Tables and 5 Figures)

Abstract: Four groups, each of 20 chickens were vaccinated with an inactivated egg drop syndrome (EDS) vaccine. The vaccine was produced utilizing 4 variables for virus propagation. These were embryonated duck eggs, duck embryo fibroblast cell culture, chicken embryo fibroblast cell culture and chicken embryo rough cell culture (CER). An initial dose (I/M) of 0.5 ml was given per bird at the age of 2 months, boostered 3 weeks later with the same dose. A 12 weeks period of studying the acquired humoral immune response revealed a great approximation in neutralizing antibody and haemagglutination inhibition titres in different groups. Variability of cell-mediated immune response results was found as of lymphocyte transformation and phagocytic activity tests performed through a one month period post initial vaccination. On the basis of immunity studies, all variables were of approximate results, even though chicken embryo fibroblast cell culture gave the most sustainable titres through 9 passages.
Publication year 2006
Pages 625-641
Availability location معهد بحوث الامصال واللقاحات البيطرية
Availability number
Organization Name
City assiut
serial title 12th scientific congress
Author(s) from ARC
Agris Categories Animal diseasesMiscellaneous animal disordersVeterinary science and hygiene - General aspects
AGROVOC
TERMS		 Cell culture. Ducks. Egg drop syndrome. Eggs. Vaccines.
Publication Type Conference/Workshop
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