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The Effect of Natural Infection with Some Blood Parasites and their Treatment on the Humoral and Cell Mediated Immunity of PPR Vaccine in Sheep
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Abstract: Egypt exports the peste des petits ruminants (PPR) vaccine to several arab, African and Asian countries, where the PPR is rampant. However, the simultaneous blood parasitic diseases, which are considered immunosuppressive agents are widespread among sheep and goats. The purpose of our work is to study the effect of theileriosis and babesiosis and their treatment with Butalex and Imizol respectively, on the immune response of vaccinated sheep with PPR vaccine.
The naturally infected groups of sheep with T. ovis and B. ovis showed a tendency of lower antibody responses in comparison with the uninfected group, post vaccination, as determined by the serum neutralization test (SNT). In addition, a depression in the cell mediated immunity was apparent between 3-7 days post vaccination (PV).
Complete clinical recovery and improvements in the blood profile were obtained in the treated animals where the packed cell volume (PCV), the haemoglobin content (Hb) as well as the lymphocytic count were accentuated gradually to reach their normal values.
The two aforementioned drugs were satisfactory used in the treatment of the blood parasites simultaneously with vaccination with the PPR vaccine
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| Publication year |
2005
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| Pages |
49-57
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| Availability location |
معهد بحوث الامصال واللقاحات البيطرية
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| Availability number |
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| Organization Name |
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| City |
الزقازيق
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| serial title |
faculty of vet. medicine
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| ISSN |
1110-1458
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| Author(s) from ARC |
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| Agris Categories |
Animal diseases
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AGROVOC
TERMS |
Vaccines.
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| Proposed Agrovoc |
PPR Vaccine in Sheep;Sheep-Diseases;
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| Publication Type |
Journal
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