Trials to improve the immune response of live newcastle disease vaccine
Abstract: Three experiments were designed to study the effect of addition of both DEAE dextran and casein hydrolysate in different concentrations to the live Newcastle disease (ND) vaccine each alone before lyophilization and as a constituent of the vaccinal diluent during vaccination. Also, their effect on the virus propagation in embryonated chicken eggs (ECEs) were studied. The obtained results revealed that the addition of 100 μg /ml DEAE dextran to the vaccinal diluent gave the higher HI titre and 100% protection after challenge 4 weeks post vaccination followed by the group given 50μg/ml. In case of addition of 1 and 2 % casein hydrolysate before lyophilization of ND vaccine give the higher haemagglutination inhibition (HI) titre after 4 weeks post vaccination and 100 % protection. The results of infection of the same concentration of both substances revealed their effect on the virus propagation in the ECEs.
Publication year 2000
Pages 73-81
Availability location معهد بحوث الامصال واللقاحات البيطرية
Availability number
Organization Name
City منصورة
serial title faculty of veterinarymedicine mansoura university
ISSN 1110-7219
Author(s) from ARC
Agris Categories Animal diseasesMiscellaneous animal disorders
AGROVOC
TERMS		 Casein. Dextrans. Newcastle disease. Newcastle disease virus. Vaccines.
Publication Type Journal
↑