Use of BCG vaccine for enhancement the immune response of sheep to Rev.1 vaccination
Abstract: This study was conducted to evaluate the protective effect of Brucella melitensis Rev.1 and the use of BCG vaccine as immunostimulant by subcutaneous injection in Guinea pigs. Lab. Animals were divided into 8 groups : Combined Rev.1 and BCG vaccines injected in the 1st group & both vaccines were injected simultaneously in the 2nd group. Three groups sensitized with BCG vaccine then injected with Rev.1 vaccine one week, two week & three weeks intervals respectively. Other two groups were injected with BCG and Rev.1 vaccine individually. The last one was unvaccinated control. All injected animals showed resistance to infection with 16 M strain (90%, 80%, 60%, 70 %, 0% and 70 % respectively) Thus animals vaccinated with bivalent Rev.1 and BCG vaccines (in one shot) showed the best protective level to infection.
Publication year 2007
Pages 6-11
Availability location معهد بحوث الامصال واللقاحات البيطرية
Availability number
Organization Name
City beni-suef
serial title the fifth scintific conference beni-suef university faculty of veterinary medicine
Author(s) from ARC
Agris Categories Animal diseasesMiscellaneous animal disordersVeterinary science and hygiene - General aspects
AGROVOC
TERMS		 Brucella. Brucella melitensis. Immune response. Sheep. Vaccines.
Publication Type Conference/Workshop
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