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Immunological studies on simultaneous vaccination with pneumo-3 and ppr inactivated vaccine in sheep
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Abstract: Atotal of twelve seronegative sheep, against infectious bovine thinotracheitis (IBR), bovine viral diarrhoea (BVD) and parainfluenza-3 (PI-3) and pest des petits ruminants (PPR) viruses were randomly divided into four groups(each group consists of 3 sheep).the first group, received simultaneous vaccination with pneumo-3 and inactivated ppr vaccines, while the second group received pneumo-3 and inactivated PPr vaccines, while the second group received pneumo-3 vaccine and after 2 weeks that received inactivated PPr vaccine. the third group received firstly the inactivated PPR vaccine, then received inactivated pneumo-3 vaccine after2 weeks, while the fourth group was kept as non-vaccinated control group. all tested animals remained clinically normal throughout the whole experimental period. very satisfactory serological responses were detected in animals, simultaneously vaccinated with both vaccines. no differences were detected in serum neutralizing antibody titres against IBR,BVD,PI-3 and PPR viruses, in sheep which received inacivated PPR vaccine, neither before nor after vaccination with pneumo-3 vaccine . the results clearly indicated the safety and efficacy of simultaneous vaccination of sheep with pneumo-3 and inactivated PPr vaccine without any competition for the response to individual vaccin. also there is neither synergistic nor antagonistic effect forthe two vaccines in sheep
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Publication year |
2007
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Pages |
37- 47
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Availability location |
معهد بحوث الامصال واللقاحات البيطرية
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Availability number |
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Organization Name |
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City |
اسيوط
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serial title |
faculty of veterinary medicine
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Author(s) from ARC |
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Agris Categories |
Animal diseasesVeterinary science and hygiene - General aspects
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AGROVOC TERMS |
Immunological factors.
Pest of small ruminants.
Sheep.
Vaccines.
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Publication Type |
Journal
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