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Influences of viral antigen distribution on the potency of inactivated oil emulsion Newcastle disease vaccine
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Abstract: The relationship between antigen distribution in the external outer phase and internal water in oil (W/O) phase of inactivated Newcastle disease virus (NDV) vaccine was studied. Four batches were prepared with antigen content 100%, 75%, 50% and 25% of the internal W/O phase. The vaccines were evaluated after experimental vaccination of four equally groups of susceptible chicks. Vaccine evaluation depended mainly upon the haemagglutination inhibition (HI) and challenge test. Vaccine batch number 3 that prepared with 50% antigen content in both the external and internal (W\O) phase was more potent as a high HI antibody titer and a good protection percentage was obtained, and this study proved that this ratio of antigen distribution was preferably for preparation of water in oil in water inactivated NDV vaccine
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| Publication year |
2007
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| Pages |
61-71
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| Availability location |
معهد بحوث الامصال واللقاحات البيطرية
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| Availability number |
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| Organization Name |
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| City |
Cairo
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| serial title |
Procceding of the2nd scientific congress
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| Author(s) from ARC |
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| External authors (outside ARC) |
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| Agris Categories |
Animal diseases
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AGROVOC
TERMS |
Antigens.
Emulsions.
Newcastle disease.
Newcastle disease virus.
Vaccines.
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| Publication Type |
Conference/Workshop
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