The role of equine herps -1 antisera in preventing abortion in laboratory animals as a ‎model

Abstract: The study was designated to detect the efficacy of passive protection using immune ‎serum against local strains of EHV-1 to prevent abortion in susceptible mares, so the ‎laboratory animals (mice, rabbits) used as a model. Preparation of the immune sera was ‎done using different types of viral antigens. Experimentally, it was clear that inactivated ‎‎(at 56° C) egg propagated viral antigen was better than tissue culture antigen. Also, ‎transfer of 0.2 and 0.3 ml polyclonal hyperimmune serum protected 75% and 100% of ‎inoculated mice respectively after challenge. While, 1 ml was protect inoculated rabbits. ‎In conclusion, transfer of immune serum against EHV-1 succeedded to prevent abortion ‎in laboratory animals at last third of pregnancy. This is a step to be tested it in mares‎
Publication year 2007
Pages 123-133
Availability location مكتبة معهد بحوث الامصال واللقاحات البيطرية.
Availability number
Organization Name
City المنصورة
serial title المؤتمر العلمى الخامس لكلية الطب البيطرى بالمنصورة
Author(s) from ARC
AGROVOC
TERMS
Laboratory animals.
Proposed Agrovoc Immune serums;Horses Diseases;Horses Reproduction;
Publication Type Conference/Workshop