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The role of equine herps -1 antisera in preventing abortion in laboratory animals as a model
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Abstract: The study was designated to detect the efficacy of passive protection using immune serum against local strains of EHV-1 to prevent abortion in susceptible mares, so the laboratory animals (mice, rabbits) used as a model. Preparation of the immune sera was done using different types of viral antigens. Experimentally, it was clear that inactivated (at 56° C) egg propagated viral antigen was better than tissue culture antigen. Also, transfer of 0.2 and 0.3 ml polyclonal hyperimmune serum protected 75% and 100% of inoculated mice respectively after challenge. While, 1 ml was protect inoculated rabbits. In conclusion, transfer of immune serum against EHV-1 succeedded to prevent abortion in laboratory animals at last third of pregnancy. This is a step to be tested it in mares
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Publication year |
2007
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Pages |
123-133
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Availability location |
مكتبة معهد بحوث الامصال واللقاحات البيطرية.
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Availability number |
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Organization Name |
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City |
المنصورة
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serial title |
المؤتمر العلمى الخامس لكلية الطب البيطرى بالمنصورة
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Author(s) from ARC |
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AGROVOC TERMS |
Laboratory animals.
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Proposed Agrovoc |
Immune serums;Horses Diseases;Horses Reproduction;
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Publication Type |
Conference/Workshop
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