The effect of some anticoccidal drugs on the immune response of rabbits experimentally infected with Eimeria Stiedai and vaccinated with enterotoxaemia anl bloat vaccine.
Abstract: This study was performed to investigate the effect of rabbit coccidiosis and its treatment on the immune response of rabbits to enterotoxaemia and bloat vaccine. Six groups of healthy new Zealand rabbits (10 rabbits/group) were used; the first group was vaccinated with clostridial enterotoxaemia bloat vaccine, the second group vaccinated with colstridial enterotoxaemia bloat vaccine and infected with Eimeria stiedai oocysts, the third group vaccinated with enterotoxaemia bloat vaccine, infected with Eimeria stiedai oocysts and treated with semduramycin, the fourth group vaccinated, infected with Eimeria stiedai oocysts and treated with diclazuril; the fifth group did not vaccinated and infected with Eimeria stiedai oocysts, while the sixth group was left as non- vaccinated, non- infected control. The obtained results revealed that rabbits infected with Eimeria oocysts, vaccinated with clostridial blot vaccine and did not receive any treatment had the lowest antibody titer to enterotoxaemia bloat vaccine, by the use of serum neutralization test. The infected rabbits, vaccinated and treated with semduramycin or diclazuril showed better immune response than the untreated vaccinated rabbits. The highest antibody titer was recorded in rabbits which received vaccine alone. These findings reflect the importance of rabbit treatment against coccidiosis to obtain a good immune response and prevent vaccination failure with enterotoxaemia bloat vaccine.
Publication year 2009
Organization Name
City القاهرة
serial title مجلة الجمعية الطبية البيطرية المصرية لعلم الطفيليات
ISSN 1687-2274
Author(s) from ARC
Agris Categories Animal diseases
Publication Type Journal
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