Immune responses of camels to vaccination with Brucella abortus S19vaccine

Abstract: Throughout the present work, the humeral and cellular immune responses to Brucella Abortus19 (S19) vaccine were evaluated in camels. In a group of 10 camels of about 6 months of age, dose of 6.2x109 CFU was inoculated subcutaneously in each camel while a group of another 5 camels was kept without vaccination as control. Rose Bengal test (RBT) revealed that vaccinated camels began to response to S19 vaccine by the 2nd week post – vaccination showing detectable antibody levels that began to decrease by the 12th week post – vaccination to reach a zero level by 22nd week post – vaccination. The results of indirect ELISA and complement fixation test (CFT) indicated such observation while non vaccinated animals remain sero- negative allover the experimental period. It was noticed that camel cellular immune response to B. Abortus S19 vaccine showed gradual increase through 10 weeks post- vaccination but this response still poor as expected during this period. This study showed that camel behave as cattle for both humeral and cellular immune response to B. Abortus S19 vaccine.
Publication year 2009
Pages 158-164
Organization Name
City الزقازيق
serial title مجلة كلية الطب البيطري - جامعة الزقازيق
ISSN 1110-1458
Author(s) from ARC
External authors (outside ARC)
    وليد سعد الدين عبد اللطيف المعمل المركزي للرقابة على المستحضرات البيطرية
    محمود لطفي السيد المعمل المركزي للرقابة على المستحضرات البيطرية
    محمد علي مخاريطة المعمل المركزي للرقابة على المستحضرات البيطرية
    الهام عطا الله الإبياري المعمل المركزي للرقابة على المستحضرات البيطرية
Agris Categories Animal diseases
Publication Type Journal
↑