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Nueropathy of peste des petits ruminants virus vaccine (EGYPT-87) in experimental animals
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Abstract: Thirty two suckling Swiss mice, injected intracerebrally with an attenuated strain of peste des petits ruminants virus (PPRV) and thereafter sacrified under ether narcosis at time points of 3,5,7 and 9 days post inoculation (8 animals/ time point). Pathological lesions in the brain, were examined. These lesions were in the form of congestion, hemorrhages, gliosis and encephalomalacia.
Twenty eight suckling Swiss mice, injected with PPRV though the same route and kept under keen clinical observation period of one month did not exhibit any apparent clinical moribund symptoms. The injected virus could not be rescued from the brains of sacriifed animals. The issue of PPRV (attenuated strain) replication in the central nervous system of suckling Swiss mice is discussed.
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| Publication year |
2011
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| Pages |
313-326
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| Organization Name |
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| City |
القاهرة
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| serial title |
29th Arab veterinary medical congress
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| Author(s) from ARC |
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| External authors (outside ARC) |
د/ حنان شريف الظواهري
المعمل المركزي للرقابة على المستحضرات الحيوية
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| Agris Categories |
Animal diseases
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| Publication Type |
Conference/Workshop
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