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Study the Physico-Chemical Properties and Antihyperlipidemic Activities of Garden Cress Seed Oil
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Abstract: : Garden cress (Lepidium sativum) is an annual herb, grown mainly for its seeds. Physico-chemical of oil, fatty acid composition tocopherols and total phenolic of garden cress seed oil were studied. Also, the objective of the current investigation was to evaluate the effects of feeding on garden cress oils with different levels 25, 50 and 75% on serum lipid levels in Albino rats. Thirty adult albino male rats were classified into two groups. One was fed on standard diet and kept as control group. The second of rats were fed on standard diet with cholesterol for 3 weeks to be hypercholesterolemic, and then classified into 4 groups. Total cholesterol (TC), high-density lipoprotein cholesterol (HDL-c), low-density lipoprotein cholesterol (LDL-c), and triglycerides (TG), were determined. Also, serum alanine and aspartate aminotransferase (ALT and AST) were calculated. The results showed that linolenic acid (34.8%) was the major fatty acid in garden cress seed oil followed by oleic acid (21.9%), linoleic acid (11.4%). A qualitative estimation of tocopherols in garden cress oil showed the presence of alfa(?), gama(?) and sigma (?) - tocopherol, were 957, 668 and 535 ug/g oil, respectively. The experimental animal fed with Supplemented diet of rats with garden cress seed oil significant decrease in triglycerides, total cholesterol, LDL-c, VLDL-c and (AST and ALT) enzyme compared to positive control. However, The HDL levels were marginally enhanced in the rats that were fed on different levels from garden cress oil. Therefore, the diets rich in garden cress oil have more favorable effects on the blood lipid profile and plasma lipoproteins and can be recommended for patients with dyslipidemia diseases.
[Ghada M. Youssef, Heba E. El-Ghamery and Hayam Abd-Elaziz El-Sawy. Study the Physico-Chemical Properties and Antihyperlipidemic Activities of Garden Cress Seed Oil. J Am Sci 2014;10(12):324-330]. (ISSN: 1545-1003). http://www.jofamericanscience.org. 42
Key words: Garden cress seeds, Fatty acids, Tocopherol, Hypercholesterolemic, Lipid profile
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| Publication year |
2014
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| Pages |
324-330
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| serial title |
Journal of American Science
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| Author(s) from ARC |
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| External authors (outside ARC) |
هبه ابراهيم الغمري
أخصائية تغذية بمستشفى أبو الريش
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| Publication Type |
Journal
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