Antioxidant CONSUMPTION MAY PREVENT SOME HEPATIC CARCENOMA

Abstract: The liver protection against aflatoxin with dietary antioxidant in aged rats was investigated. Beans, Phaseolus vulgaris L. contaminated with that mycotoxin . was used as food source of contamination . These aflatoxins are potent hepatotoxic and Carcinogenic metabolites produced by the fungi Aspergillus flavus . The Aflatoxin producer species used were fungus A alternate as strain 1 and A paristicus as strain 2. Thirty six male albino rats of almost 16 weeks age and 280 – g ± 8 average weight have been fed on noncontaminated and contaminated beans with or without natural. Antioxidant after the addition of the plant high protein and antioxidants semimodified Food (ACES). Lience the mycotoxin infected bean seeds administrations and their combination with dietary AO were biologically evaluated in terms of special blood enzymes, body and organ weights and organ histopathology of those rats. Special interests have been directed to the brain and liver longevity. Liver function has been elevated more times, especially with the contamination of Aspergillus paristicus. This strain aflatoxin production has dramatically abouse liver tissues. Mycotoxins therefore, may generate a massive sort of oxidative stress that initiate liver carcinoma. Dietary intervention significantly reduce the liver toxification frequently predisposed by aflatoxin. Seemingly, prevention of excessive oxidative damage and the up-role of these functional food products.
Publication year 2008
Organization Name
serial title Egypt. J. Biomed. Sci.
Author(s) from ARC
Publication Type Journal
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