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Hypoglycemic Effects of Taro Mucilage on Streptozotocine-Induced Diabetic Rats
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Abstract: ABSTRACT
In recent years, the use of foods with perceived health protective effects (i.e. functional foods) has received considerable attention for reducing disease risks. Mucilage is, in general, a water extract from some plants, a component with excellent prospects as an additive not only for the food industry, but also for other healthy and industrial uses. A numerous studies revealed that it composed of some ingredients which possessed multiples therapeutic properties on the experimental rats. With such point of views, the current study interests to separate, dehydrate the taro mucilage and utilize varied concentrations (1, 3 and 6%) of the product, in addition to 6% of whole and demucilage taro, in feeding of induced diabetes rat groups for two months. Such five groups were biologically and histologically compared with another two control groups fed on the basal diet, the first was non diabetes and the second was diabetes, negative and positive group, respectively.
The current work shows that the mucilage enhanced the deal with the diabetes disease through recovery the insulin secretion and lowered the glucose presence in rat blood serum to be close to the negative control than that fed on the other diets. The same pattern was also found in case of triglycerides and the cholesterol profile, i.e., lowered the harmful fractions, triglycerides, LDL and VLDL, and enhanced the desirable one, HDL. Liver (ALP, ALT and AST) and kidney (Uric acid, Urea and Creatinine) functions as well as lipid oxidation parameters (SOD, GSPx, GSH and TBARs) were pronounced lower in the mucilage groups than that of the other diabetic rat groups, on contrary of specific parameters of the positive group diet. On the other hand, a varied significant difference of body and organs weight, especially heart and spleen, of rats fed on the mucilage diets compared with the other groups, with no significant differences among the different mucilage concentrations. Pancreatic histological examination detected that mucilage groups, especially 3 and 6%, seemed to be close to the negative control wherein, there was no histopathological changes in relative to the other diabetic rat groups. In general, involvement of taro mucilage in diets could be managed of diabetes and is known to improve liver, kidney functions and pancreatic histological examination during diabetes rat live.
Keywords: Taro mucilage, Lipid oxidation, diabetic, liver and kidney functions, pancreatic histological examination
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| URL |
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| Publication year |
2008
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| Pages |
1-17
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| Availability location |
معهد بحوث تكنولوجيا الأغذية
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| Availability number |
مركز البحوث الزراعية - ش الجامعه - الجيزة
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| Organization Name |
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| serial title |
J.Biol.chem.Environ.sci
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| Author(s) from ARC |
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| Agris Categories |
Diet and diet-related diseasesHuman nutrition - General aspectsNutrition programmes
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| Proposed Agrovoc |
التغذية المرضية;
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| Publication Type |
Journal
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