. Effect of some antioxidants on the bioavailability of iron in rats
Abstract: Anemia based on iron deficiency is the most important disease worldwide and in Egypt. The effect of rats fed diet contained tomato and carrot powders, as source of lycopene and β-carotene, as well as lycopene dissolved in oil (LDO) and lycopene extracted by solvents (LES) were used as natural antioxidants on the bioavailability of iron were studied. Iron levels indicated by haemoglobin in rat's blood using both ferrous sulfate and ferrous gluconate were determined. Lycopene and β-carotene contents were 208 and 101 mg/100g in tomato and carrot powders respectively. Rats fed on diet contained carrot powders as a source of β-carotene showed a highly significant increase in daily body weight and total food intake. No significant differences in organs weight of liver, kidney and spleen were observed in rats fed on all diets. Results also showed that, diet contained tomato powder with ferrous gluconate was better than that with ferrous sulphate since they recorded increase in rats Hb reaching 25.22 and 19.31%, respectively. The effect of lycopene extracted by solvents or dissolved directly in sunflower oil on the bioavailability of iron in rat groups fed on diet contained ferrous sulfate caused highly increment in Hb reaching 81.30 and 61.44%, respectively. Concentration of iron in liver (mg/100g) of rat groups fed on either ferrous sulfate or ferrous gluconate plus ascorbic acid was significantly higher than that in the other tested rat groups. Iron stored in liver, kidney and spleen owing to the increasing of iron bioavailability which increased in groups of rats fed on diets contained ferrous sulphate with ascorbic acid, ferrous sulphate with lycopene extracted by solvents and ferrous sulphate with lycopene dissolved in sunflower oil.
URL
Publication year 2008
Pages 1-27
Availability location معهد بحوث تكنولوجيا الاغذية-9ش الجامعة-الجيزة
Availability number
Organization Name
City القاهرة
serial title علوم الاغذية
ISSN 1235-1687
Author(s) from ARC
Agris Categories Food science and technology
AGROVOC
TERMS		 Antioxidants. Bioavailability. Iron. Rats.
Publication Type Journal
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