Effect of khella ”Ammi visnaga L.” on nephrolithiasic kidney

Abstract: The current study is an alternative treatment using Ammi visnaga L. “khella” on nephrocalcinsis rats as a preventive agent against the development of kidney stones. The experimental was conducted in normal and nephrocalcinosis rats during 40 days. Several parameters were followed after 10, 25 and 40 days as three stages of experimental period. The parameters examined included weight of the rats at the end each of stage, water intake, urinary volume, liver functions in serum, kidney functions in serum and urine and some minerals in serum and urine. At the end of each stage, rats were killed followed by weight of organs and histopathological was studied. Also, the present study deigned to produce some products by addition Ammi visnaga L. seeds as especial foods for kidney patients which were sensory evaluated. The results show that, there are non significant differences between groups for organs weight except that of kidney of the nephrocalcinosis rats which had the highest weight compared with control rats. No significant difference between groups for liver functions. The treatments with Ammi visnaga L. show that, the water extracts were improved the kidney functions and tissues more than seeds. Also, the whole seeds were better than the ground seeds for kidney functions, tissues and urinary chemistries. Histopathological showed a slight differences in liver tissues. But, the kidney tissues resulted in, interstitial fibrosis, associated with cystic dilatation, marked vacuolations of epithelial lining and necrosis of renal tubules. The sensory evaluation showed that, the addition of water extracts to dibis, fig jam and arake juice changed the colour of product and had the lowest scores for taste.
Publication year 2009
Organization Name
City GIZA
serial title Egypt. J. Biomed. Sci
Author(s) from ARC
Publication Type Journal
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