The histopathological effects of warfarin and chlorophacinone anticoagulant rodenticides on male albino rats.

Abstract: The histopathological effects of warfarin and chlorophacinone anticoagulant rodenticides were studied on liver, kidney and testis of male albino rats Rattus norvegicus after administration of sub - lethal doses ('/,o and '/4 LDso) after 15 days post - treatment. The microscopical examination showed that there were injuries in these organs depending on the dose level. In liver, both tested compounds induced dilation of central and portal vein, congestion with lymphocytic infiltration and necrosis. In kidney , the two tested compounds occurred renal cloudy swelling, congestion, lymphocytic infiltration, focal areas of haemorrhage in the internal tubular connective tissues and necrosis. Also, the effect of the two compounds on the testis showed that there were thickness basement membrane and lymphocytic infiltration of seminiferous tubules.
Publication year 2003
Pages 5685-5698
Availability location معهد بحوث وقاية النباتات --7 شارع نادى الصيد - الدقى- الجيزة
Availability number
Organization Name
City المنصورة
serial title مجله جامعه المنصورة للعلوم الزراعية
ISSN 1110-0346
Author(s) from ARC
Agris Categories Protection of plants - General aspects
AGROVOC
TERMS
Administration. Anticoagulants. Chlorophacinone. Kidneys. Liver. Males. Rodenticides. Testes. Warfarin.
Publication Type Journal