Influence of short heat exposure, balanced feed restriction and acetic acid on gastrointestinal tract and mortality during post-weaning in rabbits with emphasis in heat shock protein
Abstract: This study was aimed to evaluate whether induction of heatshock protein 70 and 90 by short heat exposure. balanced feed restriction or acetic acid supplementation is protecting against intestinal injury that occur during weaning. Kits were weaned at 30 days of age and divided into 4 groups (each group 20 kits) as following: 1ST group: kits were kept as control (Control); 2nd group: kits were fed restricted diet (≈75% ad-libitum diet) during 1st week post weaning (Restriction); 3rd group: kits were exposed to high ambient temperature (34±2°C) for 1 hour (Heat); 4th group: kits were supplemented by 0.5 % acetic acid in drink water (Acetic).
Quantity of both mRNA heat shock protein families 70 (HSP70) and 90 (HSP 90) in jejunum was recorded with fed restricted diet compared with the other groups. Value of mRNA 90 only in jejunum of heat and acetic acid , supplemental groups was higher than that control. Activities of amylase, protease enzymes in small intestine contents of heat exposure were higher while, lipase was lower compared with those in control group. The significant reduction in N/L ratio in both of feed restriction and heat groups may be a good indicator of the increase of primary immunity. Villous height and crypt depth (pm) in mid-jejunum in control group were lower than that in other groups. In summary: Balanced feed restriction applied immediately thereafter the weaning (for one week) resulted in increasing expression of both HSP 90 and 70 which reflected on protection of the villous-crypt structure and immune function against some forms of stress. Feed restriction and shot heat exposure and acetic acid supplementation decreases the post weaning mortality rate (%) post weaning to 13.3, J3.3, and 20 respectively, vs. 33.3 in control.
Publication year 2008
Pages 299-310
Availability location معهد بحوث الانتاج الحيوانى- شارع نادى الصيد- الدقى - الجيزة
Availability number
Organization Name
City الاسكندرية
serial title Egyptian Poultry Science
ISSN 1110-5623
Author(s) from ARC
Agris Categories Animal physiology - Nutrition
AGROVOC
TERMS		 Acetic acid. Heat stress. Mortality. Postweaning period. Rabbits.
Proposed Agrovoc heatshock protein;short heat exposure;balanced feed restriction;intestinal injury;
Publication Type Journal
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