Genotype and age effects on immunity traits, corticosterone and oxidative status in growing rabbits
Abstract: To investigate the effects of genotype and age on native immunity, corticosterone and oxidative status 60 weaned rabbits were used; 30 Native Middle-Egypt rabbits (NMER) and 30 New Zealand White (NZW). Blood samples were collected and analyzed from each rabbit at 45, 60, and 75 d of age. Native immunity were included count and differential count of leukocyte, Serum Bactericidal Activity –SBA, Hemolytic complement Assay–HCA, lysozyme). Oxidative status (Reactive Oxygen Substances–ROS and total Antioxidant Capacity of plasma, TAC) were estimated in plasma. Genotype was an important source of variation (p< 0.01) for leukocytes where NMER was higher than NZW. Effect of age was not significant in Leukocytes. Genotype and age had significant (p<0.05) effect in both of Netruphile and Lymphocyte. Netruphile was increased while lymphocyte decreased at 45 d (after 10 d from weaning). Corticosterone levels at 45 days were higher than at others ages in both breeds. Breed significantly influenced Lysozyme and SBA in native immunity traits. NMER rabbits were characterized by a higher lysozyme, an increased SBA and complement when compared to NZW rabbits at different age. Lysozyme and HCA trends were higher at 45d than at 60 d, whereas the SBA increased with age. Reduced plasma levels of ROS in NMER rabbits at 60 and 75 days of age compared to NZW. TAC and ROS were significantly (p<0.05) affected by age while breed had no significant effect It can be concluded that NMER rabbits were characterized by of native immunity traits (lysozyme, SBA and complement) when compared to NZW rabbits at different ages.
Key words: Middle-Egypt rabbits, genotype, immunity, corticosterone, oxidative status, age
Publication year 2012
Pages 107-111
Availability location معهد بحوث الانتاج الحيوانى- شار ع نادى الصيد- الدقى - الجيزة
Availability number
Organization Name
City شرم الشيخ
serial title 10 th World Rabbit Congress
Author(s) from ARC
Agris Categories Animal husbandry
AGROVOC
TERMS		 Age. Genotypes. Glucocorticoids. Immune response.
Proposed Agrovoc Middle-Egypt rabbits;oxidative status;
Publication Type Conference/Workshop
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