The effect of Tamoxifen on some reproductive traits in two local chicken strains 1. precocious puberty in tamoxlfen treated cockerels
Abstract: The aim of this study was to test the effects of tamoxifen (TAM) on semen characteristics and reproductive organs by inducing precocious sexual puberty in two local chicken strains. Sixty, 3-Wk-old male chicks from each of Gimmizah and Bandarah local strains were divided into three equal groups 20 chicks each The chicks were injected intramuscularly twice a week with TAM at doses of 0.5 mg and 1 mg/kg BW respectively, while the controls were injected with 0.2 ml mixture of sunfflower oil and ethanol (1:1, v/v). The whole experimental period lasted until 16 weeks of age.
The results revealed that all groups treated with TAM had significantly (P<0.01) increased body weight especially at 11 and 15 weeks of age. Also Bandarah male chicks had heavier body weight than Gimmizah male chicks at the same period (P<0.01). The two doses of TAM also produced semen with live Spermatozoa at 7 weeks of age and significantly -eased semen Physical properties ollover experimental period (P<0.01) except PH value which was not affected with TAM treatments at 12 weeks of age. There were significant differences between the two strains in ejaculate volume, live sperm % and sperm concentration at the ages of 12 and 14 weeks (P<0.5), 10 weeks (P<0.01) and 10 and 14 weeks (P<0.05), respectively. A rise of serum testosterone content was associated with increase of relative weights of testes and comb and enhanced comb factor at 12 ond 16 weeks of age. Moreover, there was a significant decrease (P<0.01) in serum total lipids and cholesterol in the TAM treated male chicks at 12 weeks of age. Furthermore, TAM caused a significant decrease in serum calcium and relotlve weight of ohdomlnoJ jitt ot 12 and 16 weeks of age. Bandarah male chicks were lower than Gimmizah male in serum cholesterol. It is concluded that TAM treatment induces precocious puberty and improves semen characteristics in juvenile cockerels.
Publication year 2006
Pages 1057-1070
Availability location معهد بحوث الانتاج الحيوانى- شارع نادى الصيد- الدقى-الجيزة
Availability number
Organization Name
City الاسكندرية
serial title Egyptian Poultry Science
ISSN 1110-5623
Author(s) from ARC
Agris Categories Animal physiology - Reproduction
AGROVOC
TERMS		 Chickens. Ethanol. Males. Reproductive performance. Semen.
Proposed Agrovoc Tamoxifen;precocious puberty;sexual puberty;sunfflower oil;
Publication Type Journal
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