Trials for preparation and evaluation of oil inactivated vaccine against Newcastle disease, infectious bronchitis, egg drop syndrome and swollen head syndrome

Abstract: Inactivated viruses of Newcastle disease (ND), infectious brochitis(IB), egg drop syndrome(EDS)and swollen head syndrome(SHS) were incorporated into water in oil emulsion vaccine (monovalent) or as in combined (Tetarvalent vaccine). Immunological response of the new tetravalent vaccine was evaluated by injecting groups of susceptible chickens with either tetravalent or monovalent vaccines. Humoral immune response was evaluated by direct haemagglutination inhibition test for NDV and EDS virus and enzyme linked immunosorebent assay(ELISA) for SHS and IEV. Challenge test was carried out against NDV using velogenic viscerotropic newcastle disease virus (VVNDV). The results proved that the humoral immunity of teh new tetravelnt vaccine were never inferior to those obtained wiht the monovalent ones and also there is no practical differences in the percentage of the protective immunity induced with NDV. The prepared tetravalent (NDV, IBV, EDS and, SHS) inactivated vaccine was immunogenic safe and produced satifactory protection.
Publication year 2009
Pages 226-238
Availability location القاهرة - ش السكة البيضاء - العباسية
Availability number
Organization Name
City Ras sudr
serial title Third international scientific conference
Author(s) from ARC
External authors (outside ARC)
    لمياء محمد عمر
    امل احمد سيد
Agris Categories Animal diseases
AGROVOC
TERMS
Bronchitis. Newcastle disease. Symptoms. Vaccines.
Publication Type Conference/Workshop