Evaluation of immune response of pregnant ewes to simultaneous Vaccination with pneumo-4 and pneumobac vaccines

Abstract: The present study was conducted to evaluate the immune response of pregnant ewes to simultaneous vaccination with Pneumo-4 (IBR, PI-3, BVD and BRSV virus) and pneumobac (Mannheimia, haemolytica, p.trehalosi and p.multocida), in addition , to maternal immunity transferred through colostrum to their offspring. The immune response against these antigens was estimated serologically in pregnant ewes, colostrums and newly born lambs until four months of age. All vaccinated ewes either with single or simultaneous vaccination responded serologically well and exhibited significant increased in antibody titers as compared with titers of controls. Colostral antibody titers were positively associated with those of ewes at lambing and in the neonatal lambs. In conclusion pregnant ewes can be safely vaccinated through simultaneous vaccination with pneumo-4 and pneumobac vaccines to control viral and bacterial respiratory affection in newly born lambs.
Publication year 2009
Pages 133-140
Organization Name
City أسيوط
serial title المؤتمر العلمي العاشر
Author(s) from ARC
External authors (outside ARC)
    أنهار عبد المعطي السيد معهد الأمصال و اللقاحات البيطرية
    غادة محمد الصادق المعمل المركزي للرقابة علي المستحضرات الحيوية
    ابراهيم سليمان ابراهيم معهد بحوث الأمصال و اللقاحات
Agris Categories Animal diseases
Publication Type Conference/Workshop