SYNTHESIS AND CHARACTERIZATION OF SOME NEW ORGANO-COMPLEXES CONTAINING PYRIDOPYRAZOLOPYRIMIDINE DREVATIVES AND SOME THEIR APPLICATIONS ON SOME DAIRY PRODUCTS

Abstract: The present work is concerned with synthesis and characterization of new transition metal complexes with three organic ligands H2L1, H2L2 and H2L3 which donated )I, II, III( respectively having N, O donar atoms.
This thesis consists of three main chapters in addition to application part as well as English abstract, Arabic abstract and references.
The first chapter embraces on introduction on the nature and importance of the ligands for synthesis the metal complexes as well as literature survey was reported.
The second chapter is experimental part which describes the methods for preparation of organic ligands and transition metal complexes. It is also represents the different chemical, experimental tools and equipments used for preparation of this work.
The third chapter comprises the results of characterization and discussion of the obtained complexes using physico-chemical methods such as elemental analysis, spectroscopic (IR, UV), molar conductivity, magnetic moment measurements, thermal analysis and finally an applied part which were classified into two parts the first part, includes the biological activity where, because of the wide range of activities of pyridopyrazolopyrimidine drevatives, we have been interested on the most safe complexes of pyridopyrazolopyrimidin drevatives in this work which are donated (Ib, Ic, Id, IIa, IIIa) then study them as a new class for the anticancer therapy (i.e. anti leukemia) and also investigate the antimicrobial activities of pyridopyrazolopyrimidine drevatives (I, II, III) and of their metal complexes (Ia-If, IIa, IIb, IIIa, IIIb) and finally the second part contains some properties of the fermented milk (Laban Rayeb) after addition of copper and cobalt chloride complexes (Ia, Id, IIa, IIb, IIIa, IIIb) on it.
Publication year 2020
Organization Name
Country Egypt
Author(s) from ARC
Publication Type Master Thesis