Studies on vaccine preparation for Babesia pecies infecting Egyptian sheep

Abstract: The aim of the present work was to study the application of two types of killed Babesia ovis vaccines as well as the effect of these vaccines on teh immune response of sheep against B.ovis. The vaccinated animals showed some change in the haematological picture post challenge. Slight rise in the body temprature as well as low percentage of parastemia (1-2%) were observed in the vaccinated animals post challenge. The non vaccinated challenged control animals, showed that the body temperature recorded their high values (4oC-41oc) at the 6th day post challenge. The maximum percenatge of parasitaemia for the non vaccinated challenged animals was 6%. Sharp decrease in haematological parameters. An elevation in the antibody titres of the vaccinated and challenged animals was noticed by using ELISA and IFA techniques. It was obvious form theses results that the merozoite vaccine seemed to be greater protection to sheep than the lysate one. Furthermore, it was also noticed that the sero diagnosis carried out on the vaccinated sheep revealed higher titres by using ELISA test by IFA test.
Publication year 1997
Availability location معهد بحوث الامصال و اللقاحات البيطرية - القاهرة - ش السكة البيضاء - العباسية.
Availability number
Organization Name
Country Egypt
Author(s) from ARC
External authors (outside ARC)
    أ.د.زين العابدين عبده محمد رئيس قسم بحوث وانتاج اللقاحات الطفيلية-معهد بحوث انتاج اللقاحات البيطرية
    أ.د. السيد اسماعيل حسن رمضان(استاذ الطفيليات - كلية طب بيطري - جامعة القاهرة)
    أ.د.محمد سعيد سليمان (أستاذ الطفيليات و نائب رئيس جامعة القاهرة فرع الفيوم)
Agris Categories Animal diseasesPests of animals
AGROVOC
TERMS
Babesia bovis. Disease control. Elisa. Sheep. Vaccines.
Publication Type Master Thesis