In-vivo Combined Effect of Cypermethrin and Diodo Laser Irradiation: Comet Assay Measuremets of DNA Damage in Rat Liver Cells
Abstract: In the present work, he in-vivo combined effect of the pesticide cypermethrin and 650 nm diode laser irradiation o DNA of rat liver cells was studied. The DNA damage were detected via comet assay after exposure to different combined treatments of diode laser -640-660 m- and the pesticide. the cobinatio of cypermethrin treatmet with laser irradiation showed a synergistic effect of both low dose level of cypermethrin, with high dose of diode laser. The produced combined effect might occure via enhanced mechanism. Such combined exposure may serve as environmental risk factor. The implies the storage of the pesticide in dark containers. In addition, there is a need for permanent bio-monitoring of subjects occupationally exposed to various mixtures of different environmental agents, in order to detect early genetic biomarkers of exposure and to prevent further induction of DNA legends, which could include neoplstic grwth of damaged somatic cells.
Publication year 2005
Pages 1-21
Availability location CAPLuser(المعمل المركزى للمبيدات)
Availability number
Organization Name
serial title Arab Journal of Biotechnology
Department Mammalian Toxicology
Author(s) from ARC
External authors (outside ARC)
    منى عبد العزيز عبد الكريم المعهد القومى لعلوم الليزر، جامعة القاهرة
    يحى عبد الحميد بدر المعهد القومى لعلوم الليزر، جامعة القاهرة
Agris Categories Pests of plants
AGROVOC
TERMS		 Cypermethrin. DNA. Pesticides. Rodenticides.
Publication Type Journal
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