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Preparation of combined equine influenza and Tetanus Toxoid vaccine
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تحضير لقاح مركب من أنفلونزا الخيول و توكسيد اليتانوس
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Abstract: Inactivated equine influenza from local isolate and tetanus toxoid (EITT) vaccine adjuvanted with saponin was prepared. It was inoculated into Guinea pigs as preliminary evaluation for its potency, which exceeds the permissible protective level allowed to be used for vaccination of horses. The vaccine proved to be safe and potent for horses and Guinea pigs. The mean haemagglutination inhibition (HI) antibody titres (3 weeks post vaccination) were 704 and 200 and the mean toxin neutralization (TN) antibodies (2 weeks after boostering) were 37.9 and 45 IU/ml respectively. The antibody titre in vaccinated horses was monitored up to 6 months post revaccination. The keeping quality of the prepared vaccine was studied for one year. It was found to be stable when stored at 4°C.
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| Publication year |
2011
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| Pages |
353-363
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| Organization Name |
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| serial title |
veterinary medical journal
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| Author(s) from ARC |
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| External authors (outside ARC) |
ابراهيم محمد أحمد سليمان
معهد بحوث الأمصال و اللقاحات البيطرية
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| Agris Categories |
Animal diseases
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| Publication Type |
Journal
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